[ASC-media] SA Wed 22 Oct - using genetically engineered plants to produce oral vaccines

Clare Peddie clare_peddie at hotmail.com
Thu Oct 9 10:47:44 EST 2003


(This message has been sent on behalf of Belinda Barr from the Australian 
Centre for Plant Functional Genomics Pty Ltd)

On Wednesday 22nd of October, in the Plant Research Centre Auditorium 
Professor Charles J. Arntzen will be giving a seminar entitled “Expression 
of immunogenic proteins in plants to create Oral Vaccines”

Throughout this talk, Professor Artntzen will discuss the concept of using 
genetically engineered plants to produce oral vaccines. He will provide 
examples of his research and then be available for questions and 
discussions. An interview / photo opportunity can also be organised.

Professor Charlie Arntzen is among the most distinguished of American 
scientists.  He is Director of the Arizona Biomedical Institute, a member of 
President George W Bush’s Council of Advisors on Science & Technology, a 
member of the US National Academy of Sciences and the recipient of numerous 
US national and international awards.  He has held several highly 
prestigious and senior research positions including being Director of 
Biotechnology Research for the Du Pont corporation.  He serves on the Boards 
and/or Scientific Advisory Panels for a number of prominent corporations and 
is a Board member of many senior US Government panels.

Professor Arntzen is touring Australian research centres as holder of the 
2003 Selby Traveling Fellowship. The aim of this tour is to enable Prof. 
Arntzen to interact with Australian colleagues and decision-makers and to 
convey to the wider Australian community the tremendous achievements and 
potential for GMO technologies for human health, worldwide and especially in 
developing nations.

If you wish to organise a meeting/interview time with Professor Arntzen on 
Wednesday 22nd October please contact:
Dr Ian Dry - CSIRO Plant Industry on  83038632  or  e-mail: ian.dry at csiro.au

See seminar notice below.

I then look forward to seeing you on the 22nd for this informative and 
interesting talk.

Kind regards

Belinda Barr
Communications and Education Manager
Australian Centre for Plant Functional Genomics Pty Ltd
Office GN11, Waite Building, Urrbrae SA 5064
Ph : 61 8 8303 67 25
or : 0403 294 830
Postal address : PMB 1, Glen Osmond SA 5064
belinda.barr at adelaide.edu.au

**********************************************
SEMINAR

Expression of immunogenic proteins in plants to create Oral Vaccines

Professor Charlie Arntzen
Presidential Chair and Director
Arizona Biomedical Institute
Arizona State University

"Oral vaccines are a convenient and potentially safer means of implementing 
universal vaccination programs in the developing world (as well as in 
economically advanced countries). Edible vaccines that are heat stable, easy 
to administer and cheap to produce have the potential to redress many of the 
production, distribution and delivery limitations faced by traditional 
vaccines. Research by our team, conducted over the last decade, has 
validated the concept of using genetically engineered plants to produce oral 
vaccines that induce immune responses when plant samples are eaten either 
before or after plant tissue processing.  I will discuss examples of 
research that have lead to improvements in the expression of "virus-like 
particles" with improved immunogenicity and enhanced levels of accumulation 
in plant tissues.  Protein engineering to achieve mucosal targeting of 
immunogens and the potential of oral adjuvants for improvements of 
plant-delivered vaccines will also be covered, with special emphasis on the 
expression of subunits of Cholera toxin or the heat labile enterotoxin of E. 
coli. I will also present the results of three human clinical trials using 
these “pharmacrops” which have validated the concept of oral immunization 
when the plant samples are simply eaten as food."


PLANT RESEARCH CENTRE AUDITORIUM
Hartley Grove, Waite Campus
Wednesday 22nd October at 11.30am

Professor Charles J. Arntzen is among the most distinguished of American 
scientists.  Among his many distinctions he is Director of the Arizona 
Biomedical Institute, a member of President George W Bush’s Council of 
Advisors on Science & Technology, a member of the US National Academy of 
Sciences and the recipient of numerous US national and international awards. 
  He has held several highly prestigious and senior research positions 
including being Director of Biotechnology Research for the Du Pont 
corporation.    He serves on the Boards and/or Scientific Advisory Panels 
for a number of prominent corporations and is a Board member of many senior 
US Government panels.  Professor Arntzen is touring Australian research 
centres as holder of the 2003 Selby Traveling Fellowship. The aim of this 
tour is to enable Professor Arntzen to interact with Australian colleagues 
and decision-makers and to convey to the wider Australian community the 
tremendous achievements and potential for GMO technologies for human health, 
worldwide and especially in developing nations.

_________________________________________________________________
Hot chart ringtones and polyphonics. Go to  
http://ninemsn.com.au/mobilemania/default.asp




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